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Document Type
Rapid Review
Review Code
EOC011101 RR
Question Submitted
January 11, 2021
Date Completed
January 13, 2021
Status
3. Completed
Research Team
EOC
Document Type
Rapid Review
Review Code
EOC011101 RR
Question Submitted
January 11, 2021
Date Completed
January 13, 2021
Status
3. Completed
Research Team
EOC
Key Findings
Overall, data are insufficient to recommend for or against the use of ECMO in patients with COVID-19 and refractory hypoxemia.
The best available evidence points to an overall combined mortality rate of 46% among COVID-19 patients placed on ECMO (n=331). This rate is similar to the overall 40% mortality rate for extracorporeal life support in pulmonary failure. However, mortality rates among COVID-19 patients on ECMO range widely due to patient factors, site specific factors, and small sample sizes in available studies.
Recommendations for strategies and patient indications/contraindications are available to help guide centres intending to offer ECMO to COVID-19 patients.
Category
Clinical Management
Healthcare Services
Subject
Critical Care
Treatment
Population
All
Clinical Setting
ICU
Priority Level
Level 2 One week (7 days)
Cite As
Vanstone, J; Groot, G; Dalidowicz, M; Young, C. What are the outcomes of ECMO and COVID, particularly in small centers? 2021 Jan 13; Document no.: EOC011101 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 7 p. (CEST rapid review report)
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Document Type
Rapid Review
Review Code
EOC052102 RR
Question Submitted
May 21, 2020
Date Completed
May 22, 2020
Status
3. Completed
Research Team
EOC
Document Type
Rapid Review
Review Code
EOC052102 RR
Question Submitted
May 21, 2020
Date Completed
May 22, 2020
Status
3. Completed
Research Team
EOC
Key Findings
· There was no source of Canadian data (published or grey, federal or provincial) to address this question and differentiate between types of ventilation. · There are several studies available assessing the proportions seen in other countries and a lot of theoretical literature about using non-invasive ventilation (NIV) as a first-line intervention to hopefully avoid intubation and invasive mechanical ventilation (IMV), for which there is weak evidence. · Key studies include an analysis of 36 ICU patients in Wuhan in which 41.7% received NIV and 47.2% received MIV. Another large-scale study of 1,099 hospitalized patients reported IMV in 6.1% with no report of NIV.
Category
Administration
Clinical Management
Subject
Ventilation
Health Planning
Population
All
Clinical Setting
ICU
Priority Level
Level 3 completed within 2-3 days
Cite As
Badea, A; Groot, G; Dalidowicz, M; Miller, L. In similar jurisdictions experiencing the COVID-19 pandemic, what is the proportion of patients receiving non-invasive ventilation versus those receiving intermittent mandatory ventilation? 2020 May 22; Document no.: EOC052102 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 8 p. (CEST rapid review report)
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