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What are the differences in the clinical course of COVID-19 between patients undergoing chemotherapy and otherwise healthy individuals? [Update]

https://covid19evidencereviews.saskhealthauthority.ca/en/permalink/coviddoc248
Document Type
Rapid Review
Review Code
EOC062201v2 RR
Question Submitted
June 22, 2020
Date Completed
January 22, 2021
Status
5. Updated review
Research Team
EOC
More detail
Document Type
Rapid Review
Review Code
EOC062201v2 RR
Question Submitted
June 22, 2020
Date Completed
January 22, 2021
Status
5. Updated review
Research Team
EOC
Updated Key Findings
Generally speaking, data indicate that adult cancer patients and those who have recently received or are receiving anti-cancer therapy are at a higher risk of severe outcomes and death resulting from COVID-19 compared to those without cancer. However, more data are beginning to elucidate the nuances of these risks depending on patient specific factors.
Limited data indicate that pediatric cancer patients are not at a high level of risk of severe outcomes from COVID-19.
Limited evidence indicates some differences in the course and severity of SARS-CoV-2 infection depending on the type of immunosuppressive therapy a patient receives.
Key Findings
Generally speaking, data indicate that adult cancer patients and those who have recently received or are receiving anti-cancer therapy are at a higher risk of severe outcomes and death resulting from COVID-19 compared to those without cancer.
Pediatric cancer populations may not be at the same level of risk as adult populations.
There is not enough evidence at this time to determine if there are differences in the course of SARS-CoV-2 infection in patients receiving chemotherapy vs. those who are not aside from outcomes and severity.
Category
Clinical Presentation
Subject
Chemotherapy
Cancer
Comorbidities
Natural History
Population
All
Priority Level
Level 3 completed within 2-3 days
Cite As
Vanstone, J; Groot, G; Miller, L; Mueller, M. What are the differences in the clinical course of COVID-19 between patients undergoing chemotherapy and otherwise healthy individuals? 2021 Jan 22; Document no.: EOC062201v2 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 5 p. (CEST rapid review report)
Review History
EOC062201 RR: June 29, 2020
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What are the differences in the clinical course of COVID-19 between patients undergoing chemotherapy and otherwise healthy individuals? [Update]

https://covid19evidencereviews.saskhealthauthority.ca/en/permalink/coviddoc261
Document Type
Table
Review Code
EOC062201v2 RR Table
Question Submitted
June 22, 2020
Date Completed
January 22, 2021
Status
5. Updated review
Research Team
EOC
More detail
Document Type
Table
Review Code
EOC062201v2 RR Table
Question Submitted
June 22, 2020
Date Completed
January 22, 2021
Status
5. Updated review
Research Team
EOC
Category
Clinical Presentation
Subject
Chemotherapy
Cancer
Comorbidities
Natural History
Population
All
Priority Level
Level 3 completed within 2-3 days
Cite As
Vanstone, J; Groot, G; Miller, L; Mueller, M. What are the differences in the clinical course of COVID-19 between patients undergoing chemotherapy and otherwise healthy individuals? 2021 Jan 22; Document no.: EOC062201v2 RR Table. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 5 p. (CEST table)
Review History
EOC062201 RR: June 29, 2020
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What are the differences in the clinical course of COVID-19 between patients undergoing chemotherapy and otherwise healthy individuals? [Update]

https://covid19evidencereviews.saskhealthauthority.ca/en/permalink/coviddoc232
Document Type
Evidence Search Report
Review Code
EOC062201v2-01 ESR
Question Submitted
June 22, 2020
Date Completed
January 4, 2021
Status
5. Updated review
Research Team
EOC
More detail
Document Type
Evidence Search Report
Review Code
EOC062201v2-01 ESR
Question Submitted
June 22, 2020
Date Completed
January 4, 2021
Status
5. Updated review
Research Team
EOC
Category
Clinical Presentation
Subject
Comorbidities
Chemotherapy
Cancer
Natural History
Population
All
Priority Level
Level 3 completed within 2-3 days
Cite As
Miller, L.; Mueller, M. What are the differences in the clinical course of COVID-19 between patients undergoing chemotherapy and otherwise healthy individuals? 2021 Jan 4; Document no.: EOC062201v2 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 46 p. (CEST evidence search report)
Review History
EOC062201 RR: June 29, 2020
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What is the evidence that runny nose or sneezing are symptoms of COVID-19?

https://covid19evidencereviews.saskhealthauthority.ca/en/permalink/coviddoc182
Document Type
Rapid Review
Review Code
EOC092401 RR
Question Submitted
September 24, 2020
Date Completed
September 29, 2020
Status
3. Completed
Research Team
EOC
More detail
Document Type
Rapid Review
Review Code
EOC092401 RR
Question Submitted
September 24, 2020
Date Completed
September 29, 2020
Status
3. Completed
Research Team
EOC
Key Findings
· The significance of rhinorrhea as a presenting/predictive clinical feature of COVID-19 is unclear at this time with rates ranging from as low as 2% to as high as 60% in the published literature · Rhinorrhea generally associated with less severe disease · No reports of sneezing as a clinical symptom of COVID-19
Category
Clinical Presentation
Administration
Subject
Symptoms
Screening
Population
All
Clinical Setting
Community
Priority Level
Level 2 One week (7 days)
Cite As
Badea, A; Groot, G; Howell-Spooner, B; Young, C. What is the evidence that runny nose or sneezing are symptoms of COVID-19? 2020 Sep 29; Document no.: EOC092401 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 16 p. (CEST rapid review report)
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What is the evidence that runny nose or sneezing are symptoms of COVID-19?

https://covid19evidencereviews.saskhealthauthority.ca/en/permalink/coviddoc179
Document Type
Evidence Search Report
Review Code
EOC092401-01 ESR
Question Submitted
September 24, 2020
Date Completed
September 25, 2020
Status
3. Completed
Research Team
EOC
More detail
Document Type
Evidence Search Report
Review Code
EOC092401-01 ESR
Question Submitted
September 24, 2020
Date Completed
September 25, 2020
Status
3. Completed
Research Team
EOC
Category
Clinical Presentation
Administration
Subject
Symptoms
Screening
Population
All
Clinical Setting
Community
Priority Level
Level 2 One week (7 days)
Cite As
Young, C; Howell-Spooner, B. What is the evidence that runny nose or sneezing are symptoms of COVID-19? 2020 Sep 25; Document no.: EOC092401-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 37 p. (CEST evidence search report)
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What are the risk factors for severity and death associated with COVID-19?

https://covid19evidencereviews.saskhealthauthority.ca/en/permalink/coviddoc87
Document Type
Rapid Review
Review Code
EPM050901 RR
Question Submitted
May 9, 2020
Date Completed
May 19, 2020
Status
3. Completed
Research Team
Epidemiology & Modelling
More detail
Document Type
Rapid Review
Review Code
EPM050901 RR
Question Submitted
May 9, 2020
Date Completed
May 19, 2020
Status
3. Completed
Research Team
Epidemiology & Modelling
Key Findings
There is a growing body of research related to clinical characteristics and prognostic factors associated with COVID-19-related outcomes.
The risk of severe COVID-19 infection and mortality increases with advancing age, male sex and presence of comorbid conditions such as diabetes mellitus, hypertension and cardiovascular disease.
Information is limited about some risk factors such as smoking exposure, racial/ethnic identity that could contribute to better understanding of risk stratification and support early intervention.
Category
Clinical Presentation
Subject
Risk
Mortality
Comorbidities
Population
All
Priority Level
Level 3 completed within 2-3 days
Cite As
Williams-Roberts, H; Groot, G; Dalidowicz, M; Young, C; Mueller, M. What are the risk factors for severity and death associated with COVID-19? 2020 May 17; Document no.: EPM050901 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 14 p. (CEST rapid review report)
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Risk estimates for clinical factors predicting severity and/ or mortality associated with COVID-19

https://covid19evidencereviews.saskhealthauthority.ca/en/permalink/coviddoc89
Document Type
Table
Review Code
EPM050901 RR Table
Question Submitted
May 9, 2020
Date Completed
May 19, 2020
Status
3. Completed
Research Team
Epidemiology & Modelling
More detail
Document Type
Table
Review Code
EPM050901 RR Table
Question Submitted
May 9, 2020
Date Completed
May 19, 2020
Status
3. Completed
Research Team
Epidemiology & Modelling
Category
Clinical Presentation
Subject
Comorbidities
Risk
Mortality
Population
All
Priority Level
Level 3 completed within 2-3 days
Cite As
Williams-Roberts, H; Groot, G; Dalidowicz, M; Young, C; Mueller, M. What are the risk factors for severity and death associated with COVID-19? 2020 May 17; Document no.: EPM050901 RR Table. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. (CEST table)
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What are the risk factors for severity and death associated with COVID-19?

https://covid19evidencereviews.saskhealthauthority.ca/en/permalink/coviddoc79
Document Type
Evidence Search Report
Review Code
EPM050901-01 ESR
Question Submitted
May 9, 2020
Date Completed
May 12, 2020
Status
3. Completed
Research Team
Epidemiology & Modelling
More detail
Document Type
Evidence Search Report
Review Code
EPM050901-01 ESR
Question Submitted
May 9, 2020
Date Completed
May 12, 2020
Status
3. Completed
Research Team
Epidemiology & Modelling
Category
Clinical Presentation
Subject
Risk
Mortality
Comorbidities
Population
All
Priority Level
Level 3 completed within 2-3 days
Cite As
Dalidowicz, M; Young, C; Mueller, M. What are the risk factors for severity and death associated with COVID-19? 2020 May 12; Document no.: EPM050901-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 48 p. (CEST evidence search report)
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8 records – page 1 of 1.