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Document Type
Evidence Search Report
Review Code
LAB040802v3-01 ESR
Question Submitted
April 8, 2020
Date Completed
June 2, 2020
Status
5. Updated review
Research Team
Laboratory
Document Type
Evidence Search Report
Review Code
LAB040802v3-01 ESR
Question Submitted
April 8, 2020
Date Completed
June 2, 2020
Status
5. Updated review
Research Team
Laboratory
Category
Diagnostics
Administration
Subject
Testing
Serology
Polymerase Chain Reaction
Health Personnel
Population
All
Priority Level
Level 2 completed within 8 hours
Cite As
Duncan, V; Howell-Spooner, B. What proportion of healthcare workers are rt-PCR positive and IgM or IgG positive? 2020 Jun 2; Document no.: LAB040802v3-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 22 p. (CEST evidence search report)
Review History
LAB040802v2 RR: May 19, 2020
LAB040802 RR: April 9, 2020
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LAB040802v3-01 ESR

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Document Type
Rapid Review
Review Code
LAB040802v3 RR
Question Submitted
April 8, 2020
Date Completed
June 2, 2020
Status
5. Updated review
Research Team
Laboratory
Document Type
Rapid Review
Review Code
LAB040802v3 RR
Question Submitted
April 8, 2020
Date Completed
June 2, 2020
Status
5. Updated review
Research Team
Laboratory
Key Findings
Several references provide estimates of the proportion of HCW infected with SARS-CoV2 that range from 0.9% -20%. A recent review from Alberta Health Services that examined the COVID-19 rt-PCR test results among HCW indicates that in that province 2.4% of physicians and 0.9% of non-MD HCW who were tested were positive for SARS-CoV-2 compared to 3.5% of the general population.
In the studies reviewed, the majority of cases are confirmed by RT-PCR, while only one reference also used serology testing.
Category
Diagnostics
Administration
Subject
Testing
Serology
Polymerase Chain Reaction
Health Personnel
Population
All
Priority Level
Level 2 completed within 8 hours
Cite As
Vanstone, J; Reeder, B; Duncan, V; Howell-Spooner, B. What proportion of healthcare workers are rt-PCR positive and IgM or IgG positive? 2020 Jun 2; Document no.: LAB040802v3 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 10 p. (CEST rapid review report)
Review History
LAB040802v2 RR: May 19, 2020
LAB040802 RR: April 9, 2020
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Document Type
Supplementary
Review Code
EOC081401 SR
Question Submitted
August 14, 2020
Date Completed
August 14, 2020
Status
5. Updated review
Research Team
EOC
Document Type
Supplementary
Review Code
EOC081401 SR
Question Submitted
August 14, 2020
Date Completed
August 14, 2020
Status
5. Updated review
Research Team
EOC
Category
Administration
Infection Prevention and Control
Subject
Saskatchewan
Reopening
Schools
Priority Level
Level 4 completed within 1 week
Cite As
Muhajarine N, McRae D, Pisolkar V, et al. Saskatchewan’s school re-opening plan in comparison to other provincial plans and federal recommendations. 2020 Aug 14; Document no.: EOC081401 SR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 34 p. (CEST Summary Report)
Review History
EOC081401 RR: August 24, 2020
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Document Type
Evidence Search Report
Review Code
EOC062201v2-01 ESR
Question Submitted
June 22, 2020
Date Completed
January 4, 2021
Status
5. Updated review
Research Team
EOC
Document Type
Evidence Search Report
Review Code
EOC062201v2-01 ESR
Question Submitted
June 22, 2020
Date Completed
January 4, 2021
Status
5. Updated review
Research Team
EOC
Category
Clinical Presentation
Subject
Comorbidities
Chemotherapy
Cancer
Natural History
Population
All
Priority Level
Level 3 completed within 2-3 days
Cite As
Miller, L.; Mueller, M. What are the differences in the clinical course of COVID-19 between patients undergoing chemotherapy and otherwise healthy individuals? 2021 Jan 4; Document no.: EOC062201v2 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 46 p. (CEST evidence search report)
Review History
EOC062201 RR: June 29, 2020
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EOC062201v2-01 ESR

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Document Type
Rapid Review
Review Code
EOC062201v2 RR
Question Submitted
June 22, 2020
Date Completed
January 22, 2021
Status
5. Updated review
Research Team
EOC
Document Type
Rapid Review
Review Code
EOC062201v2 RR
Question Submitted
June 22, 2020
Date Completed
January 22, 2021
Status
5. Updated review
Research Team
EOC
Updated Key Findings
Generally speaking, data indicate that adult cancer patients and those who have recently received or are receiving anti-cancer therapy are at a higher risk of severe outcomes and death resulting from COVID-19 compared to those without cancer. However, more data are beginning to elucidate the nuances of these risks depending on patient specific factors.
Limited data indicate that pediatric cancer patients are not at a high level of risk of severe outcomes from COVID-19.
Limited evidence indicates some differences in the course and severity of SARS-CoV-2 infection depending on the type of immunosuppressive therapy a patient receives.
Key Findings
Generally speaking, data indicate that adult cancer patients and those who have recently received or are receiving anti-cancer therapy are at a higher risk of severe outcomes and death resulting from COVID-19 compared to those without cancer.
Pediatric cancer populations may not be at the same level of risk as adult populations.
There is not enough evidence at this time to determine if there are differences in the course of SARS-CoV-2 infection in patients receiving chemotherapy vs. those who are not aside from outcomes and severity.
Category
Clinical Presentation
Subject
Chemotherapy
Cancer
Comorbidities
Natural History
Population
All
Priority Level
Level 3 completed within 2-3 days
Cite As
Vanstone, J; Groot, G; Miller, L; Mueller, M. What are the differences in the clinical course of COVID-19 between patients undergoing chemotherapy and otherwise healthy individuals? 2021 Jan 22; Document no.: EOC062201v2 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 5 p. (CEST rapid review report)
Review History
EOC062201 RR: June 29, 2020
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Document Type
Table
Review Code
EOC062201v2 RR Table
Question Submitted
June 22, 2020
Date Completed
January 22, 2021
Status
5. Updated review
Research Team
EOC
Document Type
Table
Review Code
EOC062201v2 RR Table
Question Submitted
June 22, 2020
Date Completed
January 22, 2021
Status
5. Updated review
Research Team
EOC
Category
Clinical Presentation
Subject
Chemotherapy
Cancer
Comorbidities
Natural History
Population
All
Priority Level
Level 3 completed within 2-3 days
Cite As
Vanstone, J; Groot, G; Miller, L; Mueller, M. What are the differences in the clinical course of COVID-19 between patients undergoing chemotherapy and otherwise healthy individuals? 2021 Jan 22; Document no.: EOC062201v2 RR Table. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 5 p. (CEST table)
Review History
EOC062201 RR: June 29, 2020
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EOC062201v2 RR Table

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6 records – page 1 of 1.