· Well established that older individuals, particularly those with pre-existing conditions are at increased risk of severe disease and/or complications with SARS-CoV-2 infection, and volunteers should take this into consideration
· No other evidence specific to healthcare workers or volunteers to guide age restriction policies
Badea, A; Groot, G; Miller, L; Mueller, M. What are the age restrictions for healthcare workers/volunteer? 2020 Oct 19; Document no.: EOC100801 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 8 p. (CEST rapid review report)
Evidence to date of adverse events associated with mRNA COVID-19 vaccines are largely local reactions such as pain and swelling of the injection site, and systemic reactions of an allergic nature
Increased incidences of myocarditis and pericarditis have been observed, most often occurring in men under 30 years of age, and most often after the second dose of mRNA vaccine, with more occurrences following the Moderna COVID-19 vaccine versus Pfizer, however all cases appear to resolve
To date, there is no evidence indicating a negative effect on the immune system from the administration of multiple doses of mRNA COVID-19 vaccines
Badea, A; Reeder, B; Groot, G; Miller, L; Mueller, M. What are the harmful/adverse effects of multiple doses of COVID-19 mRNA vaccines? 2022 Feb 04, Document no.: EOC220103 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2022. 10 p. (CEST rapid review report).