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Document Type
Evidence Search Report
Review Code
EOC111201-01 ESR
Question Submitted
November 12, 2020
Date Completed
November 23, 2020
Status
3. Completed
Research Team
EOC
QUESTION: Are probiotics effective for prevention or therapy of respiratory tract infections in all ages
Document Type
Evidence Search Report
Review Code
EOC111201-01 ESR
Question Submitted
November 12, 2020
Date Completed
November 23, 2020
Status
3. Completed
Research Team
EOC
Category
Clinical Management
Subject
Treatment
Population
All
Priority Level
Level 4 Three weeks (21 days)
Cite As
Mueller, M; Young, C. Are probiotics effective for prevention or therapy of respiratory tract infections in all ages? 2020 Nov 23; Document no.: EOC111201-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 7 p. (CEST evidence search report)
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Document Type
Rapid Review
Review Code
EOC111201 RR
Question Submitted
November 12, 2020
Date Completed
November 25, 2020
Status
3. Completed
Research Team
EOC
infections in all ages? Abbreviated Title: Probiotics and respiratory tract infections Review ID
Document Type
Rapid Review
Review Code
EOC111201 RR
Question Submitted
November 12, 2020
Date Completed
November 25, 2020
Status
3. Completed
Research Team
EOC
Key Findings
· Systematic reviews with pooled analysis found a statistical difference between probiotic and placebo groups in days of respiratory tract illness, number of antibiotic prescriptions and days of missed work/school · The evidence for the use of probiotics while statistically significant, is of low quality with high levels of heterogeneity · No significant difference in SAEs between groups, side effects of probiotic use mainly mild GI symptoms
Category
Clinical Management
Subject
Treatment
Population
All
Priority Level
Level 4 Three weeks (21 days)
Cite As
Badea, A; Groot, G; Mueller, M; Young, C. Are probiotics effective for prevention or therapy of respiratory tract infections in all ages? 2020 Nov 25; Document no.: EOC111201 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 13 p. (CEST rapid review report)
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Document Type
Rapid Review
Review Code
CC120301 RR
Question Submitted
December 3, 2020
Date Completed
December 10, 2020
Status
3. Completed
Research Team
Critical Care
resources appropriately to patients most in need. Triage should be considered as a last resort when all
Document Type
Rapid Review
Review Code
CC120301 RR
Question Submitted
December 3, 2020
Date Completed
December 10, 2020
Status
3. Completed
Research Team
Critical Care
Key Findings
No studies directly evaluated the association between level of surge capacity and quality of care indicators for COVID-19 patients. However, in more broad studies, the findings suggest that mortality and other adverse events increase when the strain on the intensive care capacity increases.
A tiered staffing strategy is recommended to meet surge capacity needs in the ICU: High critical care nurse to patient ratios (1:1 or 1:2) are recommended to provide high quality patient care.
There is a lack of high-quality evidence to support ICU triage protocols tailored for patients with COVID-19. Nevertheless, the protocols must be flexible, adaptable according to the availability of local resources, and effective for inter-hospital patient transfer.
While the Crisis Standards of Care (CSC) guidelines (e.g., Saskatchewan’s Critical Care Resource Allocation Framework, published on September 2020) can be used to triage newly admitted COVID-19 patients requiring critical care, there is contradicting evidence about using the Sequential Organ Failure Assessment (SOFA) score for ICU triage of patients with COVID-19.
The literature suggests the use of mathematical modeling to support capacity planning (e.g., very low, low, medium, and high intensity patient surge response)
To relieve pressure from ICUs, other types of units (e.g., Step Down Unit [SDU] or Surge Clinic) can be implemented.
Category
Administration
Healthcare Services
Subject
Health Planning
Facilities
Triage
Population
All adults
Clinical Setting
ICU
Priority Level
Level 1 2-3 days
Cite As
Azizian, A; Valiani, S; Groot, G; Badea, A; Miller, L; Howell-Spooner, B. At what level of surge capacity do quality of care indicators suffer? 2020 Dec 10; Document no.: CC120301 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 17 p. (CEST rapid review report)
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Document Type
Table
Review Code
CC120301 RR Table
Question Submitted
December 3, 2020
Date Completed
December 10, 2020
Status
3. Completed
Research Team
Critical Care
with electronic medical record data of all patients with laboratory-confirmed COVID-19 admitted to intensive care
Document Type
Table
Review Code
CC120301 RR Table
Question Submitted
December 3, 2020
Date Completed
December 10, 2020
Status
3. Completed
Research Team
Critical Care
Category
Administration
Healthcare Services
Subject
Health Planning
Facilities
Triage
Population
All adults
Clinical Setting
ICU
Priority Level
Level 1 2-3 days
Cite As
Azizian, A; Valiani, S; Groot, G; Badea, A; Miller, L; Howell-Spooner, B. At what level of surge capacity do quality of care indicators suffer? 2020 Dec 10; Document no.: CC120301 RR Table. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 17 p. (CEST table)
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CC120301 RR Table

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Document Type
Evidence Search Report
Review Code
CC120301-01 ESR
Question Submitted
December 3, 2020
Date Completed
December 4, 2020
Status
3. Completed
Research Team
Critical Care
databases including MEDLINE, CINAHL, Cochrane Central, and EMBASE. All studies were appraised by at least
Document Type
Evidence Search Report
Review Code
CC120301-01 ESR
Question Submitted
December 3, 2020
Date Completed
December 4, 2020
Status
3. Completed
Research Team
Critical Care
Category
Administration
Healthcare Services
Subject
Health Planning
Facilities
Triage
Population
All adults
Clinical Setting
ICU
Priority Level
Level 1 2-3 days
Cite As
Miller, L; Howell-Spooner, B. At what level of surge capacity do quality of care indicators suffer? 2020 Dec 4; Document no.: CC120301-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 50 p. (CEST evidence search report)
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Document Type
Evidence Search Report
Review Code
LAB041402-01 ESR
Question Submitted
April 14, 2020
Date Completed
April 14, 2020
Status
3. Completed
Research Team
Laboratory
archived.YesI understand that all clinical trials and any other prospective interventional studies must
Document Type
Evidence Search Report
Review Code
LAB041402-01 ESR
Question Submitted
April 14, 2020
Date Completed
April 14, 2020
Status
3. Completed
Research Team
Laboratory
Category
Clinical Presentation
Subject
Antibodies
Natural History
Serology
Population
All
Priority Level
Level 2 completed within 8 hours
Cite As
Duncan, V. At what time in the disease timeline of COVID-19 do antibodies develop? 2020 Apr 14; Document no.: LAB041402-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 42 p. (CEST evidence search report)
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Document Type
Rapid Review
Review Code
LAB041402 RR
Question Submitted
April 14, 2020
Date Completed
April 15, 2020
Status
3. Completed
Research Team
Laboratory
. • Nearly all patients (>80%) seroconvert >15 days following the onset of symptoms. • The IgM response
Document Type
Rapid Review
Review Code
LAB041402 RR
Question Submitted
April 14, 2020
Date Completed
April 15, 2020
Status
3. Completed
Research Team
Laboratory
Key Findings
The majority of patients (>50%) appear to seroconvert between 8-14 days following the onset of symptoms.
Nearly all patients (>80%) seroconvert >15 days following the onset of symptoms.
The IgM response is detected earlier (median 12 days) than the IgG response (median 14 days).
Seroconversion appears to follow clinical recovery in most cases.
Category
Clinical Presentation
Subject
Antibodies
Natural History
Serology
Population
All
Priority Level
Level 2 completed within 8 hours
Cite As
Vanstone, J; Reeder, B; Duncan, V. At what time in the disease timeline of COVID-19 do antibodies develop? 2020 Apr 15; Document no.: LAB041402 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 4 p. (CEST rapid review report)
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Document Type
Evidence Search Report
Review Code
CC120401-01 ESR
Question Submitted
December 4, 2020
Date Completed
December 8, 2020
Status
3. Completed
Research Team
Critical Care
Protocol Better or Worse than No Protocol at All? Am J Bioeth. 2020;20(7):1-5. URL: https://dx.doi.org
Document Type
Evidence Search Report
Review Code
CC120401-01 ESR
Question Submitted
December 4, 2020
Date Completed
December 8, 2020
Status
3. Completed
Research Team
Critical Care
Category
Administration
Healthcare Services
Subject
Health Planning
Facilities
Triage
Population
All
All adults
Clinical Setting
ICU
Priority Level
Level 3 Two weeks (14 days)
Cite As
Miller, L; Howell-Spooner, B. Does data exist on the performance of triage or resource allocation frameworks for COVID-19 and other pandemics? 2020 Dec 8; Document no.: CC120401-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 20 p. (CEST evidence search report)
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Document Type
Rapid Review
Review Code
CC120401 RR
Question Submitted
December 4, 2020
Date Completed
December 17, 2020
Status
3. Completed
Research Team
Critical Care
treatments.  Creation of a central coordination body that ensures that there is optimum utilization of all
Document Type
Rapid Review
Review Code
CC120401 RR
Question Submitted
December 4, 2020
Date Completed
December 17, 2020
Status
3. Completed
Research Team
Critical Care
Key Findings
· There is little literature on the performance of triage frameworks. However, critiques of frameworks can help to inform the development of future protocols. · It is ethically problematic to include age as a triage factor rather than the more nuanced factors of frailty and chronic comorbidities. · The public should be included when creating triage protocols to create transparency and trust in the health system. · Healthcare providers should be familiar with the ethical decisions that have been made in establishing the protocols. However, using a triage team to make decisions about resource allocation would alleviate moral burden from clinicians. · Regular review of current guidelines, such as the use of SOFA scores, is recommended as knowledge about COVID-19 changes. Rapid Review Report: CC120401 RR (Version 1: December 17, 2020 11:45) 2 · Patients should be regularly reassessed to allow for timely redistribution of critical resources.
Category
Administration
Healthcare Services
Subject
Health Planning
Facilities
Triage
Population
All
All adults
Clinical Setting
ICU
Priority Level
Level 3 Two weeks (14 days)
Cite As
Fick, F; Valiani, S; Miller, L; Howell-Spooner, B. Does data exist on the performance of triage or resource allocation frameworks for COVID-19 and other pandemics? 2020 Dec 17; Document no.: CC120401 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 91 p. (CEST rapid review report)
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Document Type
Evidence Search Report
Review Code
PH061201-01 ESR
Question Submitted
June 12, 2020
Date Completed
June 12, 2020
Status
3. Completed
Research Team
Public Health
reduction in laboratory-confirmed influenza among all unimmunized community members. We assessed the impact
Document Type
Evidence Search Report
Review Code
PH061201-01 ESR
Question Submitted
June 12, 2020
Date Completed
June 12, 2020
Status
3. Completed
Research Team
Public Health
Category
Infection Prevention and Control
Subject
Communal Living
Transmission
Population
All Pediatrics
All adults
Aged (80+)
Clinical Setting
Community
Public Health
Priority Level
Level 3 completed within 2-3 days
Cite As
Howell-Spooner, B; Miller, L. How are Hutterite colonies responding to and coping with COVID-19 prevention and outbreaks? 2020 Jun 12; Document no.: PH061201-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 10 p. (CEST evidence search report)
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177 records – page 1 of 18.