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Document Type
Evidence Search Report
Review Code
EOC012001-01 ESR
Question Submitted
January 19, 2021
Date Completed
January 25, 2021
Status
3. Completed
Research Team
EOC
patients). Review ID: EOC012001-01 ESR Complete Date: January 25, 2021 Subject(s): Critical Care
Document Type
Evidence Search Report
Review Code
EOC012001-01 ESR
Question Submitted
January 19, 2021
Date Completed
January 25, 2021
Status
3. Completed
Research Team
EOC
Category
Administration
Clinical Management
Subject
Critical Care
Triage
Priority Level
Level 3 Two weeks (14 days)
Cite As
Dalidowicz, M; Fox, L. Are there validated clinical prediction tools of which Covid-19 inpatients are most probable to require ICU level care? 2021 Jan 25; Document no.: EOC012001-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 87 p. (CEST evidence search report).
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Document Type
Rapid Review
Review Code
EOC012001 RR
Question Submitted
January 19, 2021
Date Completed
February 4, 2021
Status
3. Completed
Research Team
EOC
patients with COVID-19 at high risk of critical care admission or death: An observational cohort study. J
Document Type
Rapid Review
Review Code
EOC012001 RR
Question Submitted
January 19, 2021
Date Completed
February 4, 2021
Status
3. Completed
Research Team
EOC
Key Findings
There is insufficient evidence to recommend a specific clinical prediction tool for COVID-19 patients at this time.
The 4C Mortality tool and associated risk calculator is likely the most validated prediction tool currently available.
Many tools exist and may be applied with caution, as they should be validated in the local context.
There are many patient factors included in different tools when calculating risk of disease severity.
Category
Administration
Clinical Management
Subject
Critical Care
Triage
Priority Level
Level 3 Two weeks (14 days)
Cite As
Vanstone, J; Groot, G; Dalidowicz, M; Fox, L. Are there validated clinical prediction tools of which Covid-19 inpatients are most probable to require ICU level care? 2021 Feb 4; Document no.: EOC012001 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 15 p. (CEST rapid review report)
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Document Type
Table
Review Code
EOC012001 RR Table
Question Submitted
January 19, 2021
Date Completed
February 4, 2021
Status
3. Completed
Research Team
EOC
Modelling The proposed model accurately predicts total and critical-care hospital utilization. The model
Document Type
Table
Review Code
EOC012001 RR Table
Question Submitted
January 19, 2021
Date Completed
February 4, 2021
Status
3. Completed
Research Team
EOC
Category
Administration
Clinical Management
Subject
Critical Care
Triage
Priority Level
Level 3 Two weeks (14 days)
Cite As
Vanstone, J; Groot, G; Dalidowicz, M; Fox, L. Are there validated clinical prediction tools of which Covid-19 inpatients are most probable to require ICU level care? 2021 Feb 4; Document no.: EOC012001 RR Table. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 15 p. (CEST table)
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EOC012001 RR Table

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Document Type
Evidence Search Report
Review Code
CC210301 ESR
Question Submitted
March 30, 2021
Date Completed
March 31, 2021
Status
3. Completed
Research Team
Critical Care
Cochrane Library • Comparison of Tele-Critical Care Versus Usual Care On ICU Performance (TELESCOPE
Document Type
Evidence Search Report
Review Code
CC210301 ESR
Question Submitted
March 30, 2021
Date Completed
March 31, 2021
Status
3. Completed
Research Team
Critical Care
Category
Administration
Clinical Management
Subject
Critical Care
Decision Making
Treatment
Facilities
Population
All
Clinical Setting
ICU
Priority Level
Level 1 2-3 days
Cite As
Young, C; Ellsworth, C. How to deliver remote ICU care for COVID-19 patients to avoid/prevent transfer from smaller communities to tertiary care hospitals. 2021 Mar 31; Document no.: CC210301 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 18 p. (CEST evidence search report).
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Document Type
Rapid Review
Review Code
CC210301 RR
Question Submitted
March 30, 2021
Date Completed
April 6, 2021
Status
3. Completed
Research Team
Critical Care
supporting the use of telemedicine-supported critical care, all studies were performed pre-COVID-19 pandemic
Document Type
Rapid Review
Review Code
CC210301 RR
Question Submitted
March 30, 2021
Date Completed
April 6, 2021
Status
3. Completed
Research Team
Critical Care
Key Findings
· Tele-ICU services are provided either by existing staff within the network to smaller centers, or outsourced to larger networks or independent firms · The impact of tele-ICU adoption can result in a decrease in ICU mortality as large as 32% · The impact of tele-ICU adoption of length of stay is mixed, with some studies reporting a significant decrease, while others report a small, but statistically insignificant decrease · The degree of impact of tele-ICU adoption is linked to several factors such as yearly admission rates, location (urban vs. rural) and level of authority given to the tele-ICU team leading to increased positive impacts.
Category
Administration
Clinical Management
Subject
Critical Care
Decision Making
Facilities
Treatment
Population
All
Clinical Setting
ICU
Priority Level
Level 1 2-3 days
Cite As
Badea, A; Groot, G; Reeder, B; Young, C; Ellsworth, C; Howell-Spooner, B. How to deliver remote ICU care for COVID-19 patients to avoid/prevent transfer from smaller communities to tertiary care hospitals. 2021 Apr 6; Document no.: CC210301 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 13p. (CEST rapid review report)
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Document Type
Evidence Search Report
Review Code
EOC011101-01 ESR
Question Submitted
January 11, 2021
Date Completed
January 11, 2021
Status
3. Completed
Research Team
EOC
, 2021 Interview Date: January 8, 2021 Complete Date: January 11, 2021 Subject(s): Critical Care
Document Type
Evidence Search Report
Review Code
EOC011101-01 ESR
Question Submitted
January 11, 2021
Date Completed
January 11, 2021
Status
3. Completed
Research Team
EOC
Category
Clinical Management
Healthcare Services
Subject
Critical Care
Treatment
Population
All
Clinical Setting
ICU
Priority Level
Level 2 One week (7 days)
Cite As
Dalidowicz, M; Young, C. What are the outcomes of ECMO and COVID, particularly in small centers? 2021 Jan 11; Document no.: EOC011101-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 46 p. (CEST evidence search report)
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Document Type
Rapid Review
Review Code
EOC011101 RR
Question Submitted
January 11, 2021
Date Completed
January 13, 2021
Status
3. Completed
Research Team
EOC
Document Type
Rapid Review
Review Code
EOC011101 RR
Question Submitted
January 11, 2021
Date Completed
January 13, 2021
Status
3. Completed
Research Team
EOC
Key Findings
Overall, data are insufficient to recommend for or against the use of ECMO in patients with COVID-19 and refractory hypoxemia.
The best available evidence points to an overall combined mortality rate of 46% among COVID-19 patients placed on ECMO (n=331). This rate is similar to the overall 40% mortality rate for extracorporeal life support in pulmonary failure. However, mortality rates among COVID-19 patients on ECMO range widely due to patient factors, site specific factors, and small sample sizes in available studies.
Recommendations for strategies and patient indications/contraindications are available to help guide centres intending to offer ECMO to COVID-19 patients.
Category
Clinical Management
Healthcare Services
Subject
Critical Care
Treatment
Population
All
Clinical Setting
ICU
Priority Level
Level 2 One week (7 days)
Cite As
Vanstone, J; Groot, G; Dalidowicz, M; Young, C. What are the outcomes of ECMO and COVID, particularly in small centers? 2021 Jan 13; Document no.: EOC011101 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 7 p. (CEST rapid review report)
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Document Type
Rapid Review
Review Code
CC120402 RR
Question Submitted
December 4, 2020
Date Completed
December 9, 2020
Status
3. Completed
Research Team
Critical Care
settings remains limited.  The most frequent predictors of critical care mortality integrate age
Document Type
Rapid Review
Review Code
CC120402 RR
Question Submitted
December 4, 2020
Date Completed
December 9, 2020
Status
3. Completed
Research Team
Critical Care
Key Findings
· A burgeoning body of research exists about factors associated with in-hospital mortality among COVID-19 patients; however, focus on intensive care settings remains limited. · The most frequent predictors of critical care mortality integrate age, physiologic markers and laboratory parameters in the most parsimonious models or prognostic scoring systems. · Commonly used prognostic scoring systems such as MEWS, APACHE and SOFA provide crude mortality risk prediction that may be improved with machine learning algorithms that potentially offer more clinically relevant windows and opportunities for mortality risk prediction prior to deterioration. Rapid Review Report: CC120402 RR (Version 1: December 9, 2020 14:51) 2 · Between centre variation is potentially an important determinant of critical care mortality that needs to be explored.
Category
Clinical Presentation
Subject
Critical Care
Triage
Population
All
All adults
Clinical Setting
ICU
Priority Level
Level 3 Two weeks (14 days)
Cite As
Williams-Roberts, H; Valiani, S; McLean, M; Miller, L; Howell-Spooner, B. What are the predictors of mortality in hospitalized COVID-19 patients? 2020 Dec 9; Document no.: CC120402 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 33 p. (CEST rapid review report)
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Document Type
Evidence Search Report
Review Code
CC011101-01 ESR
Question Submitted
January 8, 2021
Date Completed
January 19, 2021
Status
3. Completed
Research Team
Critical Care
? Review ID: CC011101-01 ESR Complete Date: January 19, 2021 Subject(s): Ventilation; Critical Care
Document Type
Evidence Search Report
Review Code
CC011101-01 ESR
Question Submitted
January 8, 2021
Date Completed
January 19, 2021
Status
3. Completed
Research Team
Critical Care
Category
Clinical Management
Clinical Presentation
Subject
Ventilation
Critical Care
Outcome Assessment
Population
All
Clinical Setting
ICU
Priority Level
Level 4 Three weeks (21 days)
Cite As
Fox, L; Mueller, M. What is the final disposition of post-COVID patients who require chronic ventilation in the ICU? 2021 Jan 19; Document no.: CC011101-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 51 p. (CEST evidence search report)
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Document Type
Rapid Review
Review Code
CC011101 RR
Question Submitted
January 8, 2021
Date Completed
February 27, 2021
Status
3. Completed
Research Team
Critical Care
. Critical care medicine. Retrieved from: https://www.ncbi.nlm.nih.gov/pubmed/33405409 2. Fiacchini G
Document Type
Rapid Review
Review Code
CC011101 RR
Question Submitted
January 8, 2021
Date Completed
February 27, 2021
Status
3. Completed
Research Team
Critical Care
Key Findings
There is limited research examining COVID-19 ICU patients undergoing prolonged (>14 days) mechanical ventilation
Rates of prolonged mechanical ventilation, defined as > 14 days, among COVID-19 ICU patients ranged from 16.7% to 33.3%.
Overall, studies suggest that length of ICU stay range from 11 to 31 days and length of hospital stay range from 25 to 51 days among COVID-19 patients who have undergone prolonged mechanical ventilation.
Following ICU discharge, patients are admitted to general wards, subacute nursing facilities, pneumological sub-intensive units, rehabilitation wards or long-term acute care.
Category
Clinical Management
Clinical Presentation
Subject
Ventilation
Critical Care
Outcome Assessment
Population
All
Clinical Setting
ICU
Priority Level
Level 4 Three weeks (21 days)
Cite As
Groot, G; McLean, M; Fox, L; Mueller, M. What is the final disposition of post-COVID patients who require chronic ventilation in the ICU? 2021 Feb 27; Document no.: CC011101 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 37 p. (CEST rapid review report)
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10 records – page 1 of 1.