Skip header and navigation

11 records – page 1 of 2.

Document Type
Evidence Search Report
Review Code
EOC021901v2 ESR
Question Submitted
February 19, 2021
Date Completed
October 21, 2021
Status
5. Updated review
Research Team
EOC
-19 Evidence Support Team EVIDENCE SEARCH REPORT Review Question: Long COVID: What does it mean
Document Type
Evidence Search Report
Review Code
EOC021901v2 ESR
Question Submitted
February 19, 2021
Date Completed
October 21, 2021
Status
5. Updated review
Research Team
EOC
Category
Healthcare Services
Clinical Presentation
Subject
Long Covid
Clinical Presentation
Health Planning
Symptoms
Population
All
Clinical Setting
Ambulatory
Long Term Care
Primary care
Priority Level
Level 5 Four weeks+ (28 days+)
Cite As
Mueller, M; Dalidowicz, M. Long COVID: What does it mean for the healthcare system and programs to? 2021 Oct 21, Document no.: EOC021901v2 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2021. 70 p. (CEST rapid review report).
Related Documents
Documents
Less detail
Document Type
Table
Review Code
EOC021901v2 RR Table
Question Submitted
February 19, 2021
Date Completed
October 29, 2021
Status
5. Updated review
Research Team
EOC
: Long COVID: What does it mean for the healthcare system and programs to deal with it? Review Code
Document Type
Table
Review Code
EOC021901v2 RR Table
Question Submitted
February 19, 2021
Date Completed
October 29, 2021
Status
5. Updated review
Research Team
EOC
Category
Healthcare Services
Clinical Presentation
Subject
Long Covid
Clinical Presentation
Health Planning
Symptoms
Population
All
Clinical Setting
Ambulatory
Long Term Care
Primary care
Priority Level
Level 5 Four weeks+ (28 days+)
Cite As
Williams-Roberts, H; Groot, G; Mueller, M; Dalidowicz, M. Long COVID: What does it mean for the healthcare system and programs? 2021 Oct 29. Document no.: EOC021901v2 RR Table. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2021. (CEST Table).
Related Documents
Documents

EOC021901v2 RR Table

Download File
Less detail
Document Type
Rapid Review
Review Code
EOC021901v2 RR
Question Submitted
February 19, 2021
Date Completed
October 29, 2021
Status
5. Updated review
Research Team
EOC
Support Team RAPID REVIEW REPORT Long COVID: What does it mean for the healthcare system and programs
Document Type
Rapid Review
Review Code
EOC021901v2 RR
Question Submitted
February 19, 2021
Date Completed
October 29, 2021
Status
5. Updated review
Research Team
EOC
Updated Key Findings
October 29, 2021
In October, WHO released a consensus definition of post COVID-19 condition that includes 12 domains. This development should lead to better standardization of reporting and contribute to more precise prevalence estimates and better understanding of associated risk factors.
The effects of Variants of Concern (VoC) and COVID vaccination on progression of Long COVID symptoms remains unclear.
Risk factors for developing Long COVID symptoms were similar but limited evidence suggests that pre-pandemic psychological distress and poor general health were associated with developing persistent symptoms. Evidence is too limited to determine whether vaccination reduces the risk of developing Long COVID among persons with breakthrough infections.
Given the protean manifestations of Long COVID symptoms, the underlying causes are likely multifactorial; however, strong evidence to substantiate the theories of causation remains limited.
Research related to longer-term consequences of SARS CoV-2 infections in pediatric populations is growing but remains limited.
Key Findings
March 15, 2021
There is a lack of consensus around the clinical definition of Long COVID which in turn causes challenges with understanding the incidence and prevalence as well as the potential impact for the health care system
Information about the natural history of Long COVID is incomplete but limited evidence suggests that the immune response trajectories differ for those with few or no symptoms compared to those with severe disease. Individuals with severe disease are more likely to exhibit immunological marker abnormalities but anyone can experience functional limitations.
The mechanisms underlying the development of persistent symptoms in Long COVID remain an enigma. Despite multiple theories, there is little empirical evidence for specific immunological and or biochemical abnormalities in samples of individuals with symptoms consistent with Long COVID.
Risk factors for Long COVID include female gender, older age, higher body mass index, pre-existing asthma and the number of symptoms.
Few studies explored the short-term impact of Long COVID on health care utilization patterns and found a higher impact for those with severe disease compared with mild disease.
Category
Healthcare Services
Clinical Presentation
Subject
Long Covid
Clinical Presentation
Health Planning
Symptoms
Population
All
Clinical Setting
Ambulatory
Long Term Care
Primary care
Priority Level
Level 5 Four weeks+ (28 days+)
Cite As
Williams-Roberts, H; Groot, G; Mueller, M; Dalidowicz, M. Long COVID: What does it mean for the healthcare system and programs? 2021 Oct 29. Document no.: EOC021901v2 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2021. 14 p. (CEST rapid review report).
Related Documents
Documents
Less detail
Document Type
Evidence Search Report
Review Code
EPM210602 ESR
Question Submitted
June 22, 2021
Date Completed
June 25, 2021
Status
3. Completed
Research Team
Epidemiology & Modelling
this information to make more informed predictions about long-covid Review Code: EPM210602 ESR Complete Date
Document Type
Evidence Search Report
Review Code
EPM210602 ESR
Question Submitted
June 22, 2021
Date Completed
June 25, 2021
Status
3. Completed
Research Team
Epidemiology & Modelling
Category
Clinical Presentation
Epidemiology
Subject
Long Covid
Health Planning
Clinical Presentation
Population
All
Clinical Setting
Ambulatory
Community
Emergency
ICU
Long Term Care
Medicine Unit
Primary care
Public Health
Priority Level
Level 1 2-3 days
Cite As
Howell-Spooner, B; Ellsworth, E. What are long COVID's demands on the healthcare system, and it? 2021 Jun 25, Document no.: EPM210602 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2021. 64 p. (CEST rapid review report).
Related Documents
Documents
Less detail
Document Type
Table
Review Code
EPM210602 RR Table
Question Submitted
June 22, 2021
Date Completed
July 12, 2021
Status
3. Completed
Research Team
Epidemiology & Modelling
Findings Definition of Long COVID Median age(IQR) Gender (n,%) No of patients Outcomes assessed Outcome
Document Type
Table
Review Code
EPM210602 RR Table
Question Submitted
June 22, 2021
Date Completed
July 12, 2021
Status
3. Completed
Research Team
Epidemiology & Modelling
Category
Clinical Presentation
Epidemiology
Subject
Long Covid
Health Planning
Clinical Presentation
Population
All
Clinical Setting
Ambulatory
Community
Emergency
ICU
Long Term Care
Medicine Unit
Primary care
Public Health
Priority Level
Level 1 2-3 days
Cite As
McLean, M; Williams-Roberts, H; Reeder, B; Howell-Spooner, B; Ellsworth, C. What are long COVID's demands on the healthcare system, and its severity of the illness? 2021 Jul 12, Document no.: EPM210602 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2021. (CEST table).
Related Documents
Documents

EPM210602 RR Table

Download File
Less detail
Document Type
Rapid Review
Review Code
EPM210602 RR
Question Submitted
June 22, 2021
Date Completed
July 12, 2021
Status
3. Completed
Research Team
Epidemiology & Modelling
. Key Findings  Long COVID-19 is likely to increase healthcare demands across the health system
Document Type
Rapid Review
Review Code
EPM210602 RR
Question Submitted
June 22, 2021
Date Completed
July 12, 2021
Status
3. Completed
Research Team
Epidemiology & Modelling
Key Findings
Long COVID-19 is likely to increase healthcare demands across the health system, including emergency departments, hospital admissions, primary care visits, specialists appointments, and home care and rehabilitation services.
The clinical care burden of long COVID-19 is the greatest in the first 3 months after testing and is likely to place the greatest demand on primary care services.
Patients with severe COVID-19 illness are more likely to place longer-term demands (4-6 months) on specialist care due to respiratory, circulatory, endocrine, metabolic, psychiatric and unspecified conditions.
Category
Clinical Presentation
Epidemiology
Subject
Long Covid
Health Planning
Clinical Presentation
Population
All
Clinical Setting
Ambulatory
Community
Emergency
ICU
Long Term Care
Medicine Unit
Primary care
Public Health
Priority Level
Level 1 2-3 days
Cite As
McLean, M; Williams-Roberts, H; Reeder, B; Howell-Spooner, B; Ellsworth, C. What are long COVID's demands on the healthcare system, and its severity of the illness? 2021 Jul 12, Document no.: EPM210602 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2021. 23 p. (CEST rapid review report).
Related Documents
Documents
Less detail
Document Type
Evidence Search Report
Review Code
EPM210601 ESR
Question Submitted
June 22, 2021
Date Completed
June 25, 2021
Status
3. Completed
Research Team
Epidemiology & Modelling
EVIDENCE SEARCH REPORT Review Question: What is the incidence and duration of long COVID cases
Document Type
Evidence Search Report
Review Code
EPM210601 ESR
Question Submitted
June 22, 2021
Date Completed
June 25, 2021
Status
3. Completed
Research Team
Epidemiology & Modelling
Category
Clinical Presentation
Epidemiology
Subject
Long Covid
Symptoms
Clinical Presentation
Population
All
Clinical Setting
Ambulatory
Community
ICU
Long Term Care
Medicine Unit
Primary care
Public Health
Priority Level
Level 1 2-3 days
Cite As
Howell-Spooner, B; Ellsworth, E. What is the incidence and duration of long COVID cases? 2021 Jun 25, Document no.: EPM210601 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2021. 62 p. (CEST rapid review report).
Related Documents
Documents
Less detail
Document Type
Rapid Review
Review Code
EPM210601 RR
Question Submitted
June 22, 2021
Date Completed
July 9, 2021
Status
3. Completed
Research Team
Epidemiology & Modelling
Team RAPID REVIEW REPORT What is the incidence and duration of Long COVID cases
Document Type
Rapid Review
Review Code
EPM210601 RR
Question Submitted
June 22, 2021
Date Completed
July 9, 2021
Status
3. Completed
Research Team
Epidemiology & Modelling
Key Findings
The frequency of Long COVID symptoms varies widely across studies based on populations studied, duration of follow up and methods of assessment of symptoms.
It is estimated that 1 in 50 persons experience Long COVID symptoms after 12 weeks; however, higher estimates up to 80% have been reported in studies with a greater proportion of persons who were previously hospitalized. A recent study of a mixed cohort of 96 persons found that only 22.9% had no symptoms at 12 months post diagnosis.
A wide range of symptoms affecting multiple organ systems has been reported. For many persons symptoms improve over time while others experience persistent and/or new symptoms. Among studies with the longest duration of follow up, the most frequently reported symptoms included fatigue (up to 65%), dyspnea (up to 50%), headache (up to 45%), anosmia/ageusia (up to 25%), cognitive memory/concentration (up to 39.6%) and sleep disorders (up to 26%).
Few studies estimated the duration of symptoms with estimates ranging from 2.2% for 6 months and 27% for 7-9 months.
The mechanism(s) leading to Long COVID remain unclear but those experiencing post acute sequelae tend to be older, have a greater number of symptoms during the acute phase of illness or manifest specific symptoms and live with multiple comorbid conditions such as obesity.
The lack of consensus on a definition of Long COVID contributes to marked variations in robust prevalence estimates.
Category
Clinical Presentation
Epidemiology
Subject
Long Covid
Symptoms
Clinical Presentation
Population
All
Clinical Setting
Ambulatory
Community
ICU
Long Term Care
Medicine Unit
Primary care
Public Health
Priority Level
Level 1 2-3 days
Cite As
Williams-Roberts, H; Groot, G; Reeder, B; Howell-Spooner, B; Ellsworth, C. What is the incidence and duration of Long COVID cases? 2021 Jul 09, Document no.: EPM210601 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2021. 19 p. (CEST rapid review report).
Related Documents
Documents
Less detail
Document Type
Table
Review Code
EPM210601 RR Table
Question Submitted
June 22, 2021
Date Completed
July 9, 2021
Status
3. Completed
Research Team
Epidemiology & Modelling
: What is the incidence and duration of long COVID cases? Review Code: EPM210601 RR Version: 1 Review
Document Type
Table
Review Code
EPM210601 RR Table
Question Submitted
June 22, 2021
Date Completed
July 9, 2021
Status
3. Completed
Research Team
Epidemiology & Modelling
Category
Clinical Presentation
Epidemiology
Subject
Long Covid
Symptoms
Clinical Presentation
Population
All
Clinical Setting
Ambulatory
Community
ICU
Long Term Care
Medicine Unit
Primary care
Public Health
Priority Level
Level 1 2-3 days
Cite As
Williams-Roberts, H; Groot, G; Reeder, B; Howell-Spooner, B; Ellsworth, C. What is the incidence and duration of Long COVID cases? 2021 Jul 09; Document no.: EPM210601 RR Table. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2021. (CEST table).
Related Documents
Documents

EPM210601 RR Table

Download File
Less detail
Document Type
Evidence Search Report
Review Code
EOC091601-01 ESR
Question Submitted
September 16, 2020
Date Completed
September 18, 2020
Status
3. Completed
Research Team
EOC
://patientresearchcovid19.com/ BMJ. Long covid: How to define it and how to manage it. [7 September 2020] https
Document Type
Evidence Search Report
Review Code
EOC091601-01 ESR
Question Submitted
September 16, 2020
Date Completed
September 18, 2020
Status
3. Completed
Research Team
EOC
Category
Healthcare Services
Clinical Presentation
Subject
Long Covid
Natural History
Treatment
Priority Level
Level 5 completed within 2 weeks
Cite As
Dalidowicz, M; Fox, L. What is the post acute covid syndrome and its implications in terms of health services? 2020 Sep 18; Document no.: EOC091601-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 40 p. (CEST evidence search report)
Related Documents
Documents
Less detail

11 records – page 1 of 2.