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Document Type
Evidence Search Report
Review Code
INF042401-01 ESR
Question Submitted
24-Apr-2020
Date Completed
25-Apr-2020
Status
3. Completed
Research Team
Infectious Disease
QUESTION: What is the period of communicability of symptomatic SARS-CoV-2? UNIQUE IDENTIFIER: INF042401
Document Type
Evidence Search Report
Review Code
INF042401-01 ESR
Question Submitted
24-Apr-2020
Date Completed
25-Apr-2020
Status
3. Completed
Research Team
Infectious Disease
Category
Infection Prevention and Control
Epidemiology
Subject
Transmission
Symptoms
Symptomatic
Natural History
Asymptomatic
Population
All
Priority Level
Level 3 completed within 2-3 days
Cite As
Young, C; Dalidowicz, M; Mueller, M. What is the period of communicability of symptomatic SARS-CoV-2? 2020 Apr 25; Document no.: INF042401-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 35 p. (CEST evidence search report)
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Document Type
Rapid Review
Review Code
INF042401 RR
Question Submitted
24-Apr-2020
Date Completed
April 27, 2020
Status
3. Completed
Research Team
Infectious Disease
Review Title: What is the period of communicability of symptomatic SARS CoV-2? Keyword Title
Document Type
Rapid Review
Review Code
INF042401 RR
Question Submitted
24-Apr-2020
Date Completed
April 27, 2020
Status
3. Completed
Research Team
Infectious Disease
Key Findings
The period of communicability of symptomatic SARS CoV-2 infections remains unclear.
Viral RNA shedding measured from the onset of illness is a common proxy used to estimate the period of communicability; however, confirmation of the viability of viral remnants in secretions through culture or other methods seldom occurs in practice.
Several factors including age, male sex and clinical severity influence individual variation in viral shedding and suggest the need for tailored control efforts.
Temporal patterns in viral shedding across different types of bodily secretions has implications for transmissibility and criteria for discontinuation of control measures during convalescence.
Category
Infection Prevention and Control
Epidemiology
Subject
Transmission
Symptoms
Symptomatic
Natural History
Asymptomatic
Population
All
Priority Level
Level 3 completed within 2-3 days
Cite As
Williams-Roberts, H; Lee, S; Young, C; Dalidowicz, M; Mueller, M. What is the period of communicability of symptomatic SARS CoV-2? 2020 Apr 27; Document no.: INF042401 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 24 p. (CEST rapid review report)
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Document Type
Rapid Review
Review Code
LAB040701v2 RR
Question Submitted
April 7, 2020
Date Completed
May 8, 2020
Status
5. Updated review
Research Team
Laboratory
Review Title: What proportion of disease transmission is due to asymptomatic, pre- symptomatic
Document Type
Rapid Review
Review Code
LAB040701v2 RR
Question Submitted
April 7, 2020
Date Completed
May 8, 2020
Status
5. Updated review
Research Team
Laboratory
Key Findings
COVID-19 is primarily transmitted by symptomatic patientsand presymptomatic individuals.·Moderate grade evidence estimates that approximately 20% of COVID-19 transmission may bedue to that from presymptomatic individuals.However, estimates range from 6.4% -47%.·Asymptomatic individuals and environmental contaminationappear to contributelessto disease transmission,with estimated proportionsof 6% and 10%, respectivelyfrom modelling studies
Category
Clinical Presentation
Epidemiology
Subject
Transmission
Symptoms
Symptomatic
Asymptomatic
Natural History
Population
All
Priority Level
Level 2 completed within 8 hours
Cite As
Wang, H; Reeder, B; Howell-Spooner, B; What proportion of disease transmission is due to asymptomatic, pre-symptomatic and symptomatic cases? 2020 May 8; Document no.: LAB040701v2 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 12 p. (CEST rapid review report)
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EPM051301 RR
Review History
LAB040701 RR: April 7, 2020
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Document Type
Evidence Search Report
Review Code
LAB040701v2-01 ESR
Question Submitted
April 7, 2020
Date Completed
May 8, 2020
Status
5. Updated review
Research Team
Laboratory
QUESTION: What Proportion of disease transmission is due to asymptomatic, pre-symptomatic and symptomatic
Document Type
Evidence Search Report
Review Code
LAB040701v2-01 ESR
Question Submitted
April 7, 2020
Date Completed
May 8, 2020
Status
5. Updated review
Research Team
Laboratory
Category
Clinical Presentation
Epidemiology
Subject
Transmission
Symptoms
Symptomatic
Asymptomatic
Natural History
Population
All
Priority Level
Level 2 completed within 8 hours
Cite As
Howell-Spooner, B. What proportion of disease transmission is due to asymptomatic, pre-symptomatic and symptomatic cases? 2020 May 8; Document no.: LAB040701v2-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 25 p. (CEST evidence search report)
Review History
LAB040701 RR: April 7, 2020
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LAB040701v2-01 ESR

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