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Document Type
Evidence Search Report
Review Code
EOC111201-01 ESR
Question Submitted
November 12, 2020
Date Completed
November 23, 2020
Status
3. Completed
Research Team
EOC
treatment outcome/ 1073879 15 ((treat* or therap* or intervent* or modalit* or clinical or patient
Document Type
Evidence Search Report
Review Code
EOC111201-01 ESR
Question Submitted
November 12, 2020
Date Completed
November 23, 2020
Status
3. Completed
Research Team
EOC
Category
Clinical Management
Subject
Treatment
Population
All
Priority Level
Level 4 Three weeks (21 days)
Cite As
Mueller, M; Young, C. Are probiotics effective for prevention or therapy of respiratory tract infections in all ages? 2020 Nov 23; Document no.: EOC111201-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 7 p. (CEST evidence search report)
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Document Type
Rapid Review
Review Code
EOC111201 RR
Question Submitted
November 12, 2020
Date Completed
November 25, 2020
Status
3. Completed
Research Team
EOC
) 9 14 exp treatment outcome/ 1073879 15 ((treat* or therap* or intervent* or modalit
Document Type
Rapid Review
Review Code
EOC111201 RR
Question Submitted
November 12, 2020
Date Completed
November 25, 2020
Status
3. Completed
Research Team
EOC
Key Findings
· Systematic reviews with pooled analysis found a statistical difference between probiotic and placebo groups in days of respiratory tract illness, number of antibiotic prescriptions and days of missed work/school · The evidence for the use of probiotics while statistically significant, is of low quality with high levels of heterogeneity · No significant difference in SAEs between groups, side effects of probiotic use mainly mild GI symptoms
Category
Clinical Management
Subject
Treatment
Population
All
Priority Level
Level 4 Three weeks (21 days)
Cite As
Badea, A; Groot, G; Mueller, M; Young, C. Are probiotics effective for prevention or therapy of respiratory tract infections in all ages? 2020 Nov 25; Document no.: EOC111201 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 13 p. (CEST rapid review report)
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Document Type
Evidence Search Report
Review Code
CC210301 ESR
Question Submitted
March 30, 2021
Date Completed
March 31, 2021
Status
3. Completed
Research Team
Critical Care
to guide treatment, reduce long and potentially risky trans-Pacific transports, and triage transports
Document Type
Evidence Search Report
Review Code
CC210301 ESR
Question Submitted
March 30, 2021
Date Completed
March 31, 2021
Status
3. Completed
Research Team
Critical Care
Category
Administration
Clinical Management
Subject
Critical Care
Decision Making
Treatment
Facilities
Population
All
Clinical Setting
ICU
Priority Level
Level 1 2-3 days
Cite As
Young, C; Ellsworth, C. How to deliver remote ICU care for COVID-19 patients to avoid/prevent transfer from smaller communities to tertiary care hospitals. 2021 Mar 31; Document no.: CC210301 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 18 p. (CEST evidence search report).
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Document Type
Rapid Review
Review Code
CC210301 RR
Question Submitted
March 30, 2021
Date Completed
April 6, 2021
Status
3. Completed
Research Team
Critical Care
assistance by alerting onsite staff to issues, recommending treatment and mentoring onsite staff in care
Document Type
Rapid Review
Review Code
CC210301 RR
Question Submitted
March 30, 2021
Date Completed
April 6, 2021
Status
3. Completed
Research Team
Critical Care
Key Findings
· Tele-ICU services are provided either by existing staff within the network to smaller centers, or outsourced to larger networks or independent firms · The impact of tele-ICU adoption can result in a decrease in ICU mortality as large as 32% · The impact of tele-ICU adoption of length of stay is mixed, with some studies reporting a significant decrease, while others report a small, but statistically insignificant decrease · The degree of impact of tele-ICU adoption is linked to several factors such as yearly admission rates, location (urban vs. rural) and level of authority given to the tele-ICU team leading to increased positive impacts.
Category
Administration
Clinical Management
Subject
Critical Care
Decision Making
Facilities
Treatment
Population
All
Clinical Setting
ICU
Priority Level
Level 1 2-3 days
Cite As
Badea, A; Groot, G; Reeder, B; Young, C; Ellsworth, C; Howell-Spooner, B. How to deliver remote ICU care for COVID-19 patients to avoid/prevent transfer from smaller communities to tertiary care hospitals. 2021 Apr 6; Document no.: CC210301 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 13p. (CEST rapid review report)
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Document Type
Rapid Review
Review Code
EOC042201 RR
Question Submitted
April 22, 2020
Date Completed
April 27, 2020
Status
3. Completed
Research Team
EOC
Document Type
Rapid Review
Review Code
EOC042201 RR
Question Submitted
April 22, 2020
Date Completed
April 27, 2020
Status
3. Completed
Research Team
EOC
Key Findings
Mild to moderate disease that it to be managed at home is not as well defined as severe to critical, requiring hospitalization
General consensus that the appearance of severe respiratory systems or altered consciousness are the threshold for requiring hospitalization
Most guidance for assisted monitoring is limited to LTC or other care facilities vs. home care for abled individuals
Category
Clinical Presentation
Clinical Management
Subject
Risk
Treatment
Priority Level
Level 4 completed within 1 week
Cite As
Badea, A; Groot, G; Fox, L; Miller, M. What are the classification levels for disease severity of COVID-19 and how should each level be treated? 2020 Apr 27; Document no.: EOC042201 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 10 p. (CEST rapid review report)
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Document Type
Evidence Search Report
Review Code
EOC011101-01 ESR
Question Submitted
January 11, 2021
Date Completed
January 11, 2021
Status
3. Completed
Research Team
EOC
, Treatment Protocol Filters, Limits & Exclusions: English only 2019-Current Excludes: case reports
Document Type
Evidence Search Report
Review Code
EOC011101-01 ESR
Question Submitted
January 11, 2021
Date Completed
January 11, 2021
Status
3. Completed
Research Team
EOC
Category
Clinical Management
Healthcare Services
Subject
Critical Care
Treatment
Population
All
Clinical Setting
ICU
Priority Level
Level 2 One week (7 days)
Cite As
Dalidowicz, M; Young, C. What are the outcomes of ECMO and COVID, particularly in small centers? 2021 Jan 11; Document no.: EOC011101-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 46 p. (CEST evidence search report)
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Document Type
Rapid Review
Review Code
EOC011101 RR
Question Submitted
January 11, 2021
Date Completed
January 13, 2021
Status
3. Completed
Research Team
EOC
of viral infection with SARS-CoV-2, it is important to note that ECMO does not provide a treatment
Document Type
Rapid Review
Review Code
EOC011101 RR
Question Submitted
January 11, 2021
Date Completed
January 13, 2021
Status
3. Completed
Research Team
EOC
Key Findings
Overall, data are insufficient to recommend for or against the use of ECMO in patients with COVID-19 and refractory hypoxemia.
The best available evidence points to an overall combined mortality rate of 46% among COVID-19 patients placed on ECMO (n=331). This rate is similar to the overall 40% mortality rate for extracorporeal life support in pulmonary failure. However, mortality rates among COVID-19 patients on ECMO range widely due to patient factors, site specific factors, and small sample sizes in available studies.
Recommendations for strategies and patient indications/contraindications are available to help guide centres intending to offer ECMO to COVID-19 patients.
Category
Clinical Management
Healthcare Services
Subject
Critical Care
Treatment
Population
All
Clinical Setting
ICU
Priority Level
Level 2 One week (7 days)
Cite As
Vanstone, J; Groot, G; Dalidowicz, M; Young, C. What are the outcomes of ECMO and COVID, particularly in small centers? 2021 Jan 13; Document no.: EOC011101 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 7 p. (CEST rapid review report)
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Document Type
Evidence Search Report
Review Code
EOC042201v2-01 ESR
Question Submitted
April 22, 2020
Date Completed
July 15, 2020
Status
3. Completed
Research Team
EOC
://bestpractice.bmj.com/topics/en-gb/3000168/treatment- algorithm#patientGroup-0-0 [Note]: See "Treatment Algorithm
Document Type
Evidence Search Report
Review Code
EOC042201v2-01 ESR
Question Submitted
April 22, 2020
Date Completed
July 15, 2020
Status
3. Completed
Research Team
EOC
Category
Clinical Presentation
Clinical Management
Subject
Risk
Treatment
Priority Level
Level 4 completed within 1 week
Cite As
Fox, L; Miller, L. What are the classification levels for disease severity of COVID-19 and how should each level be treated? 2020 Jul 9; Document no.: EOC042201v2-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 20 p. (CEST evidence search report)
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EOC042201v2-01 ESR

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Document Type
Evidence Search Report
Review Code
EOC091601-01 ESR
Question Submitted
September 16, 2020
Date Completed
September 18, 2020
Status
3. Completed
Research Team
EOC
: A framework for assessing early rehabilitation needs following treatment in intensive care [National Post
Document Type
Evidence Search Report
Review Code
EOC091601-01 ESR
Question Submitted
September 16, 2020
Date Completed
September 18, 2020
Status
3. Completed
Research Team
EOC
Category
Healthcare Services
Clinical Presentation
Subject
Long Covid
Natural History
Treatment
Priority Level
Level 5 completed within 2 weeks
Cite As
Dalidowicz, M; Fox, L. What is the post acute covid syndrome and its implications in terms of health services? 2020 Sep 18; Document no.: EOC091601-01 ESR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 40 p. (CEST evidence search report)
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Document Type
Rapid Review
Review Code
EOC091601 RR
Question Submitted
September 16, 2020
Date Completed
October 13, 2020
Status
3. Completed
Research Team
EOC
early rehabilitation needs following treatment in intensive care [National Post-Intensive Care
Document Type
Rapid Review
Review Code
EOC091601 RR
Question Submitted
September 16, 2020
Date Completed
October 13, 2020
Status
3. Completed
Research Team
EOC
Key Findings
· There is no consistent definition of the post-acute COVID syndrome. · There is a need to distinguish between the rehabilitation needs of severe COVID patients and the persistent collection of symptoms that occur for a variable period of time in some patients. · Individuals with severe initial infections are more likely to have ongoing symptoms · The duration of post-covid symptoms is unclear at this point in time · The common post-covid symptoms can be grouped as general, respiratory, cardiovascular, mental health, and neurologic sequelae. · A follow up review is probably warranted
Category
Healthcare Services
Clinical Presentation
Subject
Long Covid
Natural History
Treatment
Priority Level
Level 5 completed within 2 weeks
Cite As
Badea, A; Groot, G; Dalidowicz, M; Fox, L. What is the post acute covid syndrome and its implications in terms of health services? 2020 Oct 13; Document no.: EOC091601 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 28 p. (CEST rapid review report)
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