· Systematic reviews with pooled analysis found a statistical difference between probiotic and placebo groups in days of respiratory tract illness, number of antibiotic prescriptions and days of missed work/school
· The evidence for the use of probiotics while statistically significant, is of low quality with high levels of heterogeneity
· No significant difference in SAEs between groups, side effects of probiotic use mainly mild GI symptoms
Badea, A; Groot, G; Mueller, M; Young, C. Are probiotics effective for prevention or therapy of respiratory tract infections in all ages? 2020 Nov 25; Document no.: EOC111201 RR. In: COVID-19 Rapid Evidence Reviews [Internet]. SK: SK COVID Evidence Support Team, c2020. 13 p. (CEST rapid review report)